Wydanie 328(39)3 2016

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https://oa.zut.edu.pl/handle/20.500.12539/708

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Przeglądaj Wydanie 328(39)3 2016 wg Autor "Andraszek, Katarzyna"

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    PozycjaOpen Access
    Epigenetics of reproduction
    (Wydawnictwo Uczelniane Zachodniopomorskiego Uniwersytetu Technologicznego w Szczecinie, 2016) Czubaszek, Magdalena; Andraszek, Katarzyna; Banaszewska, Dorota; Department of Animal Genetics and Horse Breeding, Siedlce University of Natural Sciences and Humanities; Department of Animal Genetics and Horse Breeding, Siedlce University of Natural Sciences and Humanities; Department of Breeding Methods and Poultry and Small Ruminant Breeding, Siedlce University of Natural Sciences and Humanities
    Epigenetic research offers a significant opportunity to understand the role of environmental interactions on the genome and disease, while enabling modulation of these interactions in order to improve human health. Knowledge of both genetic and epigenetic changes is essential for identification of functional gametes and for fertility treatment. Future studies in both human and animal models may enable better understanding of the mechanisms underlying the relationship between altered DNA methylation in the sperm cell and infertility. It is currently unclear whether methylation defects found in the DNA of infertile sperm are primary or secondary defects. An understanding of what underlies DNA methylation disorders will be important for the development of successful fertility treatments. While epigenetic research will unquestionably expand our knowledge of general genetics, it is mainly valued for its innovative and comprehensive approach to molecular diagnostics and is directed towards clinical procedures.