Przeglądaj wg Autor "Czubaszek, Magdalena"

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  • Miniatura
    PozycjaOpen Access
    Epigenetics of reproduction
    (Wydawnictwo Uczelniane Zachodniopomorskiego Uniwersytetu Technologicznego w Szczecinie, 2016) Czubaszek, Magdalena; Andraszek, Katarzyna; Banaszewska, Dorota; Department of Animal Genetics and Horse Breeding, Siedlce University of Natural Sciences and Humanities; Department of Animal Genetics and Horse Breeding, Siedlce University of Natural Sciences and Humanities; Department of Breeding Methods and Poultry and Small Ruminant Breeding, Siedlce University of Natural Sciences and Humanities
    Epigenetic research offers a significant opportunity to understand the role of environmental interactions on the genome and disease, while enabling modulation of these interactions in order to improve human health. Knowledge of both genetic and epigenetic changes is essential for identification of functional gametes and for fertility treatment. Future studies in both human and animal models may enable better understanding of the mechanisms underlying the relationship between altered DNA methylation in the sperm cell and infertility. It is currently unclear whether methylation defects found in the DNA of infertile sperm are primary or secondary defects. An understanding of what underlies DNA methylation disorders will be important for the development of successful fertility treatments. While epigenetic research will unquestionably expand our knowledge of general genetics, it is mainly valued for its innovative and comprehensive approach to molecular diagnostics and is directed towards clinical procedures.
  • Miniatura
    PozycjaOpen Access
    The Role of Staining Techniques in Seminological Analysis of Mammalian Semen
    (Wydawnictwo Uczelniane Zachodniopomorskiego Uniwersytetu Technologicznego w Szczecinie, 2015) Banaszewska, Dorota; Andraszek, Katarzyna; Zdrowowicz, Ewa; Czubaszek, Magdalena; Walczak-Jędrzejowska, Renata; Institute of Bioengineering and Animal Breeding, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland; Institute of Bioengineering and Animal Breeding, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland; Institute of Bioengineering and Animal Breeding, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland; Institute of Bioengineering and Animal Breeding, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland; Department of Andrology and Reproductive Endocrinology, Medical University in Łódź, Poland
    The most important semen parameters are the concentration, motility and morphology of sperm cells. Sperm morphology is regarded as the most reliable parameter for predicting fertility in males. A problem in evaluating sperm morphology and morphometry is the lack of standardization of staining techniques. The staining procedure and reagents used can significantly affect the morphometric parameters of the sperm cell. The use of stains with different pH or osmotic pressure, as well as the duration of the procedure, may influence the shape and size of the sperm, and thus the result of the morphological evaluation of the semen. It is necessary to develop an evaluation procedure for sperm morphology and morphometry that will minimize the changes in the structure of the evaluated semen in relation to the native semen.